Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study by Evelyne Thériault, Massilia Benali, Samuel Starnino, Hugues Blain, Nicolas Goettel, Bianca Beloin-Jubinville, Amélie Marsot, Francois Lamontagne

Get full text

Dissemination bias in systematic reviews of animal research: a systematic review. by Katharina F Mueller, Matthias Briel, Daniel Strech, Joerg J Meerpohl, Britta Lang, Edith Motschall, Viktoria Gloy, Francois Lamontagne, Dirk Bassler

Get full text

Pharmacological interventions for agitated behaviours in patients with traumatic brain injury: a systematic review by Sangeeta Mehta, David Williamson, Anne Julie Frenette, Lisa D Burry, Marc Perreault, Emmanuel Charbonney, Francois Lamontagne, Marie-Julie Potvin, Jean-Francois Giguère, Francis Bernard

Get full text

Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature. by Mohamad Alshurafa, Matthias Briel, Elie A Akl, Ted Haines, Paul Moayyedi, Stephen J Gentles, Lorena Rios, Chau Tran, Neera Bhatnagar, Francois Lamontagne, Stephen D Walter, Gordon H Guyatt

Get full text

Corticosteroid Therapy in Critical Illness due to Seasonal and Pandemic Influenza by Philippe Yale, Neill KJ Adhikari, Vincent Masse, Robert A Fowler, Wei Xiong, Allison McGeer, Darlene Cann, Wallis Rudnick, Karen Green, Maureen O Meade, Louis Valiquette, François Lamontagne

Get full text

Low-value clinical practices in adult traumatic brain injury: an umbrella review protocol by Belinda J Gabbe, Henry Thomas Stelfox, Patrick Archambault, François Lauzier, Fiona Lecky, Francois Lamontagne, Michaël Chasse, Pier-Alexandre Tardif, Lynne Moore, Imen Farhat, John Kortbeek, Paule Lessard-Bonaventure, Catherine Truchon, Alexis F Turgeon

Get full text

Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

Get full text

Liberation from mechanical ventilation using Extubation Advisor Decision Support (LEADS): protocol for a multicentre pilot trial by François Lellouche, Patrick Archambault, Emma Lee, Emmanuel Charbonney, Francois Lamontagne, Alexandre Tran, David M Maslove, Alexis F Turgeon, Jim Kutsogiannis, Damon Scales, Akshai Iyengar, Christophe L Herry, Nathan B Scales, Maged Tanios, Karen E. A. Burns, Audrey Gouskos, Jill E. Allan, Marlene Santos-Taylor, Phyllis Kay, Pamela Greco, Hilary Every, Owen Mooney, Edmund Tan, Asher Mendelson, Andrew J.E. Seely, Canadian Critical Care Trials Group

Get full text

Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19 by Greg Haljan, Terry Lee, Anne McCarthy, Juthaporn Cowan, Jennifer Tsang, Francois Lelouche, Alexis F. Turgeon, Patrick Archambault, Francois Lamontagne, Robert Fowler, Jennifer Yoon, Peter Daley, Matthew P. Cheng, Donald C. Vinh, Todd C. Lee, Karen C. Tran, Brent W. Winston, Hyejin Julia Kong, John H. Boyd, Keith R. Walley, Allison McGeer, David M. Maslove, John C. Marshall, Joel Singer, Fagun Jain, James A. Russell

Get full text

Community versus academic hospital community-acquired pneumonia patients: a nested cohort study by Jennifer L.Y. Tsang, Kian Rego, Alexandra Binnie, Terry Lee, Anne Mccarthy, Juthaporn Cowan, Patrick Archambault, Francois Lellouche, Alexis F. Turgeon, Jennifer Yoon, Francois Lamontagne, Allison Mcgeer, Josh Douglas, Peter Daley, Robert Fowler, David M. Maslove, Brent W. Winston, Todd C. Lee, Karen C. Tran, Matthew P. Cheng, Donald C. Vinh, John H. Boyd, Keith R. Walley, Joel Singer, John C. Marshall, Gregory Haljan, Fagun Jain, James A. Russell, For CAPTIVATE Investigators

Get full text

Machine Learning Accurately Predicts Need for Critical Care Support in Patients Admitted to Hospital for Community-Acquired Pneumonia by George S. Chen, BSc, Terry Lee, PhD, Jennifer L.Y. Tsang, MD, Alexandra Binnie, MD, Anne McCarthy, MD, Juthaporn Cowan, MD, Patrick Archambault, MD, Francois Lellouche, MD, Alexis F. Turgeon, MD, MSc, Jennifer Yoon, MD, Francois Lamontagne, MD, Allison McGeer, MD, Josh Douglas, MD, Peter Daley, MD, Robert Fowler, MD, David M. Maslove, MD, Brent W. Winston, MD, Todd C. Lee, MD, Karen C. Tran, MD, Matthew P. Cheng, MD, Donald C. Vinh, MD, John H. Boyd, MD, Keith R. Walley, MD, Joel Singer, PhD, John C. Marshall, MD, James A. Russell, MD, for the Community-Acquired Pneumonia: Toward InnoVAtive Treatment (CAPTIVATE) Investigators

Get full text

Association of Musculoskeletal Indexes With 1-Year Outcomes After ≥ 7 Days of Mechanical VentilationTake-Home Points by Hannah Wozniak, MD, Erminio Santangelo, Micheal McInnis, Laura Dragoi, Priscila Robles, Leslie M. Chu, Andrea Matte, Margaret S. Herridge, Margaret S. Herridge, Leslie M. Chu, Andrea Matte, George Tomlinson, Linda Chan, Claire Thomas, Jan O. Friedrich, Sangeeta Mehta, Francois Lamontagne, Melanie Levasseur, Niall D. Ferguson, Neill K.J. Adhikari, Jill C. Rudkowski, Hilary Meggison, Yoanna Skrobik, John Flannery, Mark Bayley, Jane Batt, Claudia dos Santos, Susan E. Abbey, Adrienne Tan, Vincent Lo, Sunita Mathur, Matteo Parotto, Denise Morris, Linda Flockhart, Eddy Fan, Christie M. Lee, M. Elizabeth Wilcox, Najib Ayas, Karen Choong, Robert Fowler, Damon C. Scales, Tasnim Sinuff, Brian H. Cuthbertson, Louise Rose, Priscila Robles, Stacey Burns, Marcelo Cypel, Lianne Singer, Cecelia Chaparro, Chung-Wai Chow, Shaf Keshavjee, Laurent Brochard, Paul Hebert, Arthur S. Slutsky, John C. Marshall, Deborah Cook, Jill I. Cameron, Margaret S. Herridge, Leslie M. Chu: Andrea Matte, George Tomlinson, Linda Chan, Claire Thomas, Jan O. Friedrich, Sangeeta Mehta, Francois Lamontagne, Melanie Levasseur, Niall D. Ferguson, Neill K.J. Adhikari, Jill C. Rudkowski, Hilary Meggison, Yoanna Skrobik, John Flannery, Mark Bayley, Jane Batt, Claudia dos Santos, Susan E. Abbey, Adrienne Tan, Vincent Lo, Sunita Mathur, Matteo Parotto, Denise Morris, Linda Flockhart, Eddy Fan, Christie M. Lee, M. Elizabeth Wilcox, Najib Ayas, Karen Choong, Robert Fowler, Damon C. Scales, Tasnim Sinuff, Brian H. Cuthbertson, Louise Rose, Priscila Robles, Stacey Burns, Marcelo Cypel, Lianne Singer, Cecelia Chaparro, Chung-Wai Chow, Shaf Keshavjee, Laurent Brochard, Paul Hebert, Arthur S. Slutsky, John C. Marshall, Deborah Cook, Jill I. Cameron

Get full text

Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trialResearch in... by Sean W.X. Ong, Ruxandra Pinto, Asgar Rishu, Steven Y.C. Tong, Robert J. Commons, John M. Conly, Gerald A. Evans, Michael Fralick, Christopher Kandel, Philippe R.S. Lagacé-Wiens, Todd C. Lee, Sylvain A. Lother, Derek R. MacFadden, John C. Marshall, Valérie Martel-Laferrière, Michael Mayette, Emily G. McDonald, John D. Neary, Josef Prazak, Edward Raby, Adrian Regli, Benjamin A. Rogers, Stephanie Smith, Linda R. Taggart, Han Ting Wang, Terence Wuerz, Dafna Yahav, Paul J. Young, Robert A. Fowler, Nick Daneman, Nick Daneman, Asgar Rishu, Ruxandra Pinto, Benjamin Rogers, Yahya Shehabi, Rachael Parke, Deborah J. Cook, Yaseen Arabi, John Muscedere, Steven Reynolds, Richard Hall, Dhiraj Bhatia Dwivedi, Colin McArthur, Shay McGuinness, Dafna Yahav, Bryan Coburn, Anna Geagea, Pavani Das, Phillip Shin, Michael Detsky, Andrew Morris, Michael Fralick, Jeff E. Powis, Christopher Kandel, Wendy Sligl, Sean M. Bagshaw, Nishma Singhal, Emilie Belley-Cote, Richard Whitlock, Kosar Khwaja, Susan Morpeth, Alex Kazemi, Tony Williams, Derek R. MacFadden, Lauralyn McIntyre, Jennifer L.Y. Tsang, Francois Lamontagne, Alex Carignan, John Marshall, Jan O. Friedrich, Robert Cirone, Mark Downing, Christopher Graham, Joshua Davis, Erick Duan, John Neary, Gerald Evans, Basem Alraddadi, Sameera Al Johani, Claudio Martin, Sameer Elsayed, Ian Ball, François Lauzier, Alexis F. Turgeon, Henry Thomas Stelfox, John Conly, Todd C. Lee, Emily G. McDonald, Richard Sullivan, Jennifer Grant, Ilya Kagan, Paul Young, Cassie Lawrence, Kevin O'Callaghan, Matthew Eustace, Keat Choong, Pierre Aslanian, Ulrike Buehner, Tom Havey, Alexandra Binnie, Josef Prazak, Brenda Reeve, Edward Litton, Sylvain Lother, Anand Kumar, Ryan Zarychanski, Tomer Hoffman, David L. Paterson, Peter Daley, Robert J. Commons, Emmanuel Charbonney, Jean-Francois Naud, Sally Roberts, Ravindranath Tiruvoipati, Sachin Gupta, Gordon Wood, Omar Shum, Spiros Miyakis, Peter Dodek, Clement Kwok, Linda R. Taggart, Stephanie Smith, Karen Doucette, Robert A. Fowler

Get full text