Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants. by Anna Laddach, Joseph Chi Fung Ng, Franca Fraternali

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RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1. by Hendrik Huthoff, Flavia Autore, Sarah Gallois-Montbrun, Franca Fraternali, Michael H Malim

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Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspecies Apis mellifera mellifera by Vilde Leipart, Oriol Gracia Carmona, Christine Orengo, Franca Fraternali, Gro V. Amdam

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Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations. by Flavia Autore, Julien R C Bergeron, Michael H Malim, Franca Fraternali, Hendrik Huthoff

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Protein networks reveal detection bias and species consistency when analysed by information-theoretic methods. by Luis P Fernandes, Alessia Annibale, Jens Kleinjung, Anthony C C Coolen, Franca Fraternali

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Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins. by Flavia Autore, Mark Pfuhl, Xueping Quan, Aisling Williams, Roland G Roberts, Catherine M Shanahan, Franca Fraternali

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IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells by Marta Lebrusant-Fernandez, Tom ap Rees, Rebeca Jimeno, Nikolaos Angelis, Joseph C. Ng, Franca Fraternali, Vivian S.W. Li, Patricia Barral

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Tuning antibody stability and function by rational designs of framework mutations by Joseph C. F. Ng, Alicia Chenoweth, Maria Laura De Sciscio, Melanie Grandits, Anthony Cheung, Tooki Chu, Alexandra McCraw, Jitesh Chauhan, Yi Liu, Dongjun Guo, Semil Patel, Alice Kosmider, Daniela Iancu, Sophia N. Karagiannis, Franca Fraternali

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Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes. by Natalie J Prescott, Benjamin Lehne, Kristina Stone, James C Lee, Kirstin Taylor, Jo Knight, Efterpi Papouli, Muddassar M Mirza, Michael A Simpson, Sarah L Spain, Grace Lu, Franca Fraternali, Suzannah J Bumpstead, Emma Gray, Ariella Amar, Hannah Bye, Peter Green, Guy Chung-Faye, Bu'Hussain Hayee, Richard Pollok, Jack Satsangi, Miles Parkes, Jeffrey C Barrett, John C Mansfield, Jeremy Sanderson, Cathryn M Lewis, Michael E Weale, Thomas Schlitt, Christopher G Mathew, UK IBD Genetics Consortium

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