Exploring the pathway: clinical utility and open challenges of targeting BRAF alterations in biliary tract cancers and gastrointestinal malignancies by L. Weiss, D. Zhang, W.G. Kunz, S. Boeck, G. Curigliano, V. Subbiah, F. Lordick, T. Brummer, C.B. Westphalen, L. Boscolo Bielo

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SAPHIR: real-world clinical research platform for molecular testing, treatment, and clinical and patient-reported outcomes in patients with gastroesophageal cancer in Germany by K. Potthoff, T. Dechow, S. Lorenzen, A. Reinacher-Schick, A. Binninger, C. Matillon, H.-U. Siebenbach, I. Haffner, U. Hacker, H. Bläker, F. Lordick

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HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER2) IN GASTRIC CANCER (GC) (RESULTS OF THE MULTICENTER CLINICAL TRIAL) by H. C. Chung, Y-J. Bang, J. M. Xu, F. Lordick, A. Sawaki, O. Lipatov, M. Lehle, М. Pickl, J. Ruschoff, E. Van Cutsem

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European screening platform for EORTC clinical trials in advanced colorectal cancer ‘SPECTAcolor’ by G. Folprecht, M. Morfouace, M. Collienne, R. Salazar, A. Stein, E. Elez, A.D. Wagner, D. Arnold, C.H. Kohne, M. Ducreux, F. Lordick, B. Borelli, A. Stevovic, T. Gorlia, E. Fontana, D. Aust, V. Golfinopoulos, M. Moehler, S. Tejpar

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Local and central testing for HER2, PD-L1, MSI/MMR, EBV, and CLDN18.2 in advanced gastric cancer: results from the SAPHIR registry☆ by K. Potthoff, H. Bläker, T. Dechow, A. Binninger, K. Ringwald, R. de Buhr, E. von der Heyde, M.-O. Zahn, A. Nusch, S. Dörfel, H. Schulz, I. Haffner, A.K. Höhn, A. Monecke, S. Lorenzen, A. Reinacher-Schick, M. Jänicke, F. Lordick

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German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0 by M.P. Ebert, W. Fischbach, S. Hollerbach, J. Höppner, D. Lorenz, M. Stahl, M. Stuschke, O. Pech, U. Vanhoefer, C. Bruns, C. Ell, M. Follmann, U. Goerling, L. Grenacher, J. Haardt, A.H. Hölscher, R. Hummel, W.T. Knoefel, J. Körber, R. Langer, P. Lenz, F. Lordick, S. Lorenzen, A.G. Meining, J. Menzel, H.-J. Meyer, N.H. Nicolay, M. Nothacker, U. Nöthlings, H. Schmidberger, M. Schmidt, T. Seufferlein, P. Thuss-Patience, J. Trojan, A. Weimann, L. Klug, P. Lynen, T. Zhan, Q. Xiao, R. Porschen

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