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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency by Berenice Cabrera-Martinez, Josselyn E. Garcia-Perez, Ryan M. Baxter, Victor G. Lui, Tusharkanti Ghosh, Ahmet Eken, Zander Kostka-Newman, John Rhey Mhar Garcia, Jeremy Rahkola, Rachel L. Gessner, Cullen M. Dutmer, Jared Klarquist, Eric M. Pietras, Debashis Ghosh, Sara A. Johnson, Ross M. Kedl, Elena W.Y. Hsieh
Published 2025-07-01Get full text
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Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis by Kira A. Young, Mohsen Hosseini, Jayna J. Mistry, Claudia Morganti, Taylor S. Mills, Xiurong Cai, Brandon T. James, Griffin J. Nye, Natalie R. Fournier, Veronique Voisin, Ali Chegini, Aaron D. Schimmer, Gary D. Bader, Grace Egan, Marc R. Mansour, Grant A. Challen, Eric M. Pietras, Kelsey H. Fisher-Wellman, Keisuke Ito, Steven M. Chan, Jennifer J. Trowbridge
Published 2025-04-01Get full text
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