Douglas G. McMahon
Douglas G. McMahon is a professor of Biological Sciences and Pharmacology at
Vanderbilt University. McMahon has contributed several important discoveries to the field of
chronobiology and vision. His research focuses on connecting the anatomical location in the brain to specific behaviors. As a graduate student under
Gene Block, McMahon identified that the basal retinal neurons (BRNs) of the molluscan eye exhibited
circadian rhythms in spike frequency and membrane potential, indicating they are the clock neurons. He became the 1986 winner of the
Society for Neuroscience's Donald B. Lindsley Prize in
Behavioral Neuroscience for his work. Later, he moved on to investigate visual, circadian, and serotonergic mechanisms of
neuroplasticity. In addition, he helped find that constant light can desynchronize the circadian cells in the
suprachiasmatic nucleus (SCN). He has always been interested in the underlying causes of behavior and examining the long term changes in behavior and physiology in the neurological modular system. McMahon helped identifying a retrograde neurotransmission system in the retina involving the
melanopsin containing
ganglion cells and the retinal dopaminergic amacrine neurons.
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