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Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug MOv18 IgE demonstrates monomeric purity and stability by Paul Considine, Panida Punnabhum, Callum G. Davidson, Georgina B. Armstrong, Michaela Kreiner, Heather J. Bax, Jitesh Chauhan, James Spicer, Debra H. Josephs, Sophia N. Karagiannis, Gavin Halbert, Zahra Rattray
Published 2025-12-01Get full text
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Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis
Published 2025-12-01Get full text
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Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies. by Amy E Gilbert, Panagiotis Karagiannis, Tihomir Dodev, Alexander Koers, Katie Lacy, Debra H Josephs, Pooja Takhar, Jenny L C Geh, Ciaran Healy, Mark Harries, Katharine M Acland, Sarah M Rudman, Rebecca L Beavil, Philip J Blower, Andrew J Beavil, Hannah J Gould, James Spicer, Frank O Nestle, Sophia N Karagiannis
Published 2011-04-01Get full text
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Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction by Gabriel Osborn, Jacobo López-Abente, Rebecca Adams, Roman Laddach, Melanie Grandits, Heather J. Bax, Jitesh Chauhan, Giulia Pellizzari, Mano Nakamura, Chara Stavraka, Alicia Chenoweth, Lais C. G. F. Palhares, Theodore Evan, Jessica Hui Cheah Lim, Amanda Gross, Lenny Moise, Shashi Jatiani, Mariangela Figini, Rodolfo Bianchini, Erika Jensen-Jarolim, Sharmistha Ghosh, Ana Montes, Ahmad Sayasneh, Rebecca Kristeleit, Sophia Tsoka, James Spicer, Debra H. Josephs, Sophia N. Karagiannis
Published 2025-04-01Get full text
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