Ten simple rules for conducting a mendelian randomization study. by Sarah A Gagliano Taliun, David M Evans

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Woolf et al’s “GWAS by subtraction” is not useful for cross-generational Mendelian randomization studies by David M Evans, George Davey Smith, Gunn-Helen Moen

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Evaluating indirect genetic effects of siblings using singletons. by Laurence J Howe, David M Evans, Gibran Hemani, George Davey Smith, Neil M Davies

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Assessing the Role of DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio in Rheumatoid Arthritis by Srikant Ambatipudi, Gemma C. Sharp, Sarah L. N. Clarke, Darren Plant, Jonathan H. Tobias, David M. Evans, Anne Barton, Caroline L. Relton

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Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study. by Raquel Granell, A John Henderson, David M Evans, George Davey Smith, Andrew R Ness, Sarah Lewis, Tom M Palmer, Jonathan A C Sterne

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Haplotype-based analysis distinguishes maternal-fetal genetic contribution to pregnancy-related outcomes. by Amit K Srivastava, Julius Juodakis, Pol Sole-Navais, Jing Chen, Jonas Bacelis, Kari Teramo, Mikko Hallman, Pal R Njølstad, David M Evans, Bo Jacobsson, Louis J Muglia, Ge Zhang

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Cis and trans effects of human genomic variants on gene expression. by Julien Bryois, Alfonso Buil, David M Evans, John P Kemp, Stephen B Montgomery, Donald F Conrad, Karen M Ho, Susan Ring, Matthew Hurles, Panos Deloukas, George Davey Smith, Emmanouil T Dermitzakis

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Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy. by Rebecca Gilbert, Richard M Martin, David M Evans, Kate Tilling, George Davey Smith, John P Kemp, J Athene Lane, Freddie C Hamdy, David E Neal, Jenny L Donovan, Chris Metcalfe

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Genetic variation associated with differential educational attainment in adults has anticipated associations with school performance in children. by Mary E Ward, George McMahon, Beate St Pourcain, David M Evans, Cornelius A Rietveld, Daniel J Benjamin, Philipp D Koellinger, David Cesarini, Social Science Genetic Association Consortium, George Davey Smith, Nicholas J Timpson

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Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. by William M Brandler, Andrew P Morris, David M Evans, Thomas S Scerri, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Susan M Ring, John Stein, Anthony P Monaco, Joel B Talcott, Simon E Fisher, Caleb Webber, Silvia Paracchini

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Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. by Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson, Mika Kähönen, Olli Raitakari, Marika Laaksonen, Harri Sievänen, Jorma Viikari, Leo-Pekka Lyytikäinen, Dan Mellström, Magnus Karlsson, Osten Ljunggren, Elin Grundberg, John P Kemp, Adrian Sayers, Maria Nethander, David M Evans, Liesbeth Vandenput, Jon H Tobias, Claes Ohlsson

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Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. by Lavinia Paternoster, Mattias Lorentzon, Liesbeth Vandenput, Magnus K Karlsson, Osten Ljunggren, Andreas Kindmark, Dan Mellstrom, John P Kemp, Caroline E Jarett, Jeff M P Holly, Adrian Sayers, Beate St Pourcain, Nicholas J Timpson, Panos Deloukas, George Davey Smith, Susan M Ring, David M Evans, Jon H Tobias, Claes Ohlsson

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Mining the human phenome using allelic scores that index biological intermediates. by David M Evans, Marie Jo A Brion, Lavinia Paternoster, John P Kemp, George McMahon, Marcus Munafò, John B Whitfield, Sarah E Medland, Grant W Montgomery, GIANT Consortium, CRP Consortium, TAG Consortium, Nicholas J Timpson, Beate St Pourcain, Debbie A Lawlor, Nicholas G Martin, Abbas Dehghan, Joel Hirschhorn, George Davey Smith

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Association of Forced Vital Capacity with the Developmental Gene NCOR2. by Cosetta Minelli, Charlotte H Dean, Matthew Hind, Alexessander Couto Alves, André F S Amaral, Valerie Siroux, Ville Huikari, María Soler Artigas, David M Evans, Daan W Loth, Yohan Bossé, Dirkje S Postma, Don Sin, John Thompson, Florence Demenais, John Henderson, SpiroMeta consortium, CHARGE consortium, Emmanuelle Bouzigon, Deborah Jarvis, Marjo-Riitta Järvelin, Peter Burney

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Genome-wide association study identifies four loci associated with eruption of permanent teeth. by Frank Geller, Bjarke Feenstra, Hao Zhang, John R Shaffer, Thomas Hansen, Ann-Louise Esserlind, Heather A Boyd, Ellen A Nohr, Nicholas J Timpson, Ghazaleh Fatemifar, Lavinia Paternoster, David M Evans, Robert J Weyant, Steven M Levy, Mark Lathrop, George Davey Smith, Jeffrey C Murray, Jes Olesen, Thomas Werge, Mary L Marazita, Thorkild I A Sørensen, Mads Melbye

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Genome-wide population-based association study of extremely overweight young adults--the GOYA study. by Lavinia Paternoster, David M Evans, Ellen Aagaard Nohr, Claus Holst, Valerie Gaborieau, Paul Brennan, Anette Prior Gjesing, Niels Grarup, Daniel R Witte, Torben Jørgensen, Allan Linneberg, Torsten Lauritzen, Anelli Sandbaek, Torben Hansen, Oluf Pedersen, Katherine S Elliott, John P Kemp, Beate St Pourcain, George McMahon, Diana Zelenika, Jörg Hager, Mark Lathrop, Nicholas J Timpson, George Davey Smith, Thorkild I A Sørensen

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Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study. by Vincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P Kemp, Maria Nethander, Daniel Evans, John A Morris, Douglas P Kiel, Fernando Rivadeneira, Helena Johansson, Nicholas C Harvey, Dan Mellström, Magnus Karlsson, Cyrus Cooper, David M Evans, Robert Clarke, John A Kanis, Eric Orwoll, Eugene V McCloskey, Claes Ohlsson, Joelle Pineau, William D Leslie, Celia M T Greenwood, J Brent Richards

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Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. by Demetris Pillas, Clive J Hoggart, David M Evans, Paul F O'Reilly, Kirsi Sipilä, Raija Lähdesmäki, Iona Y Millwood, Marika Kaakinen, Gopalakrishnan Netuveli, David Blane, Pimphen Charoen, Ulla Sovio, Anneli Pouta, Nelson Freimer, Anna-Liisa Hartikainen, Jaana Laitinen, Sarianna Vaara, Beate Glaser, Peter Crawford, Nicholas J Timpson, Susan M Ring, Guohong Deng, Weihua Zhang, Mark I McCarthy, Panos Deloukas, Leena Peltonen, Paul Elliott, Lachlan J M Coin, George Davey Smith, Marjo-Riitta Jarvelin

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Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. by Carolina Medina-Gomez, John P Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M Evans, Denise H M Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, M Carola Zillikens, Ole K Olstad, Hou-Feng Zheng, J Brent Richards, Beate St Pourcain, Albert Hofman, Vincent W V Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M Gautvik, André G Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H Tobias, Fernando Rivadeneira

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Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. by John P Kemp, Carolina Medina-Gomez, Karol Estrada, Beate St Pourcain, Denise H M Heppe, Nicole M Warrington, Ling Oei, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, Lisa E Wolber, Sjur Reppe, Kaare Gautvik, Elin Grundberg, Bing Ge, Bram van der Eerden, Jeroen van de Peppel, Matthew A Hibbs, Cheryl L Ackert-Bicknell, Kwangbom Choi, Daniel L Koller, Michael J Econs, Frances M K Williams, Tatiana Foroud, M Carola Zillikens, Claes Ohlsson, Albert Hofman, André G Uitterlinden, George Davey Smith, Vincent W V Jaddoe, Jonathan H Tobias, Fernando Rivadeneira, David M Evans

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