David Stuart (structural biologist)

Sir David Ian Stuart (born 8 December 1953) is a Medical Research Council Professor of Structural Biology at the Wellcome Trust Centre for Human Genetics at the University of Oxford where he is also a Fellow of Hertford College, Oxford. He is best known for his contributions to the X-ray crystallography of viruses, in particular for determining the structures of foot-and-mouth disease virus, bluetongue virus and the membrane-containing phages PRD1 (the first structure of an enveloped virus) and PM2. He is also director of Instruct and Life Sciences Director at Diamond Light Source. Provided by Wikipedia
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  1. 1
    Evaluation and use of in-silico structure-based epitope prediction with foot-and-mouth disease virus.

    Evaluation and use of in-silico structure-based epitope prediction with foot-and-mouth disease virus. by Daryl W Borley, Mana Mahapatra, David J Paton, Robert M Esnouf, David I Stuart, Elizabeth E Fry

    Published 2013-01-01
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  2. 2
    The structure of an RNAi polymerase links RNA silencing and transcription.

    The structure of an RNAi polymerase links RNA silencing and transcription. by Paula S Salgado, Minni R L Koivunen, Eugene V Makeyev, Dennis H Bamford, David I Stuart, Jonathan M Grimes

    Published 2006-12-01
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  3. 3
    Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism?

    Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism? by Tobias J Tuthill, Karl Harlos, Thomas S Walter, Nick J Knowles, Elisabetta Groppelli, David J Rowlands, David I Stuart, Elizabeth E Fry

    Published 2009-10-01
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  4. 4
    The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

    The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment. by Stephen C Graham, L Peter Sarin, Mohammad W Bahar, Reg A Myers, David I Stuart, Dennis H Bamford, Jonathan M Grimes

    Published 2011-06-01
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  5. 5
    From Voxels to Viruses: Using Deep Learning and Crowdsourcing to Understand a Virus Factory

    From Voxels to Viruses: Using Deep Learning and Crowdsourcing to Understand a Virus Factory by Avery Pennington, Oliver N. F. King, Win Min Tun, Mark Boyce, Geoff Sutton, David I. Stuart, Mark Basham, Michele C. Darrow

    Published 2024-12-01
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  6. 6
    Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.

    Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure. by Yakov Korkhin, Ulug M Unligil, Otis Littlefield, Pamlea J Nelson, David I Stuart, Paul B Sigler, Stephen D Bell, Nicola G A Abrescia

    Published 2009-05-01
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  7. 7
    Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.

    Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen. by Claudine Porta, Abhay Kotecha, Alison Burman, Terry Jackson, Jingshan Ren, Silvia Loureiro, Ian M Jones, Elizabeth E Fry, David I Stuart, Bryan Charleston

    Published 2013-03-01
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  8. 8
    Rhabdovirus matrix protein structures reveal a novel mode of self-association.

    Rhabdovirus matrix protein structures reveal a novel mode of self-association. by Stephen C Graham, René Assenberg, Olivier Delmas, Anil Verma, Alireza Gholami, Chiraz Talbi, Raymond J Owens, David I Stuart, Jonathan M Grimes, Hervé Bourhy

    Published 2008-12-01
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  9. 9
    Structure and function of A41, a vaccinia virus chemokine binding protein.

    Structure and function of A41, a vaccinia virus chemokine binding protein. by Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes

    Published 2008-01-01
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  10. 10
    The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.

    The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages. by Mikael Altun, Thomas S Walter, Holger B Kramer, Patrick Herr, Alexander Iphöfer, Johan Boström, Yael David, Alia Komsany, Nicola Ternette, Ami Navon, David I Stuart, Jingshan Ren, Benedikt M Kessler

    Published 2015-01-01
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  11. 11
    Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.

    Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses. by Luigi De Colibus, Xiangxi Wang, Aloys Tijsma, Johan Neyts, John A B Spyrou, Jingshan Ren, Jonathan M Grimes, Gerhard Puerstinger, Pieter Leyssen, Elizabeth E Fry, Zihe Rao, David I Stuart

    Published 2015-10-01
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  12. 12
    Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence.

    Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence. by Carlos Maluquer de Motes, Samantha Cooray, Hongwei Ren, Gabriel M F Almeida, Kieran McGourty, Mohammad W Bahar, David I Stuart, Jonathan M Grimes, Stephen C Graham, Geoffrey L Smith

    Published 2011-12-01
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  13. 13
    Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.

    Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. by Stephen C Graham, Mohammad W Bahar, Samantha Cooray, Ron A-J Chen, Daniel M Whalen, Nicola G A Abrescia, David Alderton, Raymond J Owens, David I Stuart, Geoffrey L Smith, Jonathan M Grimes

    Published 2008-08-01
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  14. 14
    Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins.

    Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins. by Hadrien Peyret, Annick Gehin, Eva C Thuenemann, Donatienne Blond, Aadil El Turabi, Lucy Beales, Dean Clarke, Robert J C Gilbert, Elizabeth E Fry, David I Stuart, Kris Holmes, Nicola J Stonehouse, Mike Whelan, William Rosenberg, George P Lomonossoff, David J Rowlands

    Published 2015-01-01
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  15. 15
    An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters

    An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters by Yanjun Zhang, Yan Wu, Meng-Qian Zhang, Haiyue Rao, Zhaoyong Zhang, Xiangyue He, Yiwen Liang, Raoqing Guo, Yaochang Yuan, Jing Sun, Helen M. E. Duyvesteyn, Elizabeth E. Fry, David I. Stuart, Jingxian Zhao, XiaoYan Pan, Shu-Lin Liu, Jincun Zhao, Jiandong Huo

    Published 2025-05-01
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  16. 16
    Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation

    Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation by Lee Sherry, Keith Grehan, Mohammad W. Bahar, Jessica J. Swanson, Helen Fox, Sue Matthews, Sarah Carlyle, Ling Qin, Claudine Porta, Steven Wilkinson, Suzanne Robb, Naomi Clark, John Liddell, Elizabeth E. Fry, David I. Stuart, Andrew J. Macadam, David J. Rowlands, Nicola J. Stonehouse

    Published 2025-03-01
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  17. 17
    Author Correction: An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters

    Author Correction: An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters by Yanjun Zhang, Yan Wu, Meng-Qian Zhang, Haiyue Rao, Zhaoyong Zhang, Xiangyue He, Yiwen Liang, Raoqing Guo, Yaochang Yuan, Jing Sun, Helen M. E. Duyvesteyn, Elizabeth E. Fry, David I. Stuart, Jingxian Zhao, XiaoYan Pan, Shu-Lin Liu, Jincun Zhao, Jiandong Huo

    Published 2025-07-01
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  18. 18
    Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.

    Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX. by Takayoshi Shirasaki, Hui Feng, Helen M E Duyvesteyn, William G Fusco, Kevin L McKnight, Ling Xie, Mark Boyce, Sathish Kumar, Rina Barouch-Bentov, Olga González-López, Ryan McNamara, Li Wang, Adriana Hertel-Wulff, Xian Chen, Shirit Einav, Joseph A Duncan, Maryna Kapustina, Elizabeth E Fry, David I Stuart, Stanley M Lemon

    Published 2022-08-01
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  19. 19
    Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines

    Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Murdoch, Daniel Ponndorf, Seong-Ryong Kim, Sachin Shah, Sarah Carlyle, Jessica J. Swanson, Sue Matthews, Clare Nicol, George P. Lomonossoff, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart, Nicola J. Stonehouse, David J. Rowlands

    Published 2025-01-01
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