What’s new in the 2025 GOLD report by David M G Halpin, Dave Singh

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Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β2-agonist: post-hoc analyses of KRONOS by Dave Singh, Mona Bafadhel, Niki Arya, Jonathan Marshall, Himanshu Parikh, Dobrawa Kisielewicz, Charlotta Movitz, Karin Bowen, Mehul Patel

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Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate. by Jonathan Plumb, Laura Robinson, Simon Lea, Antonia Banyard, John Blaikley, David Ray, Andrea Bizzi, Giorgina Volpi, Fabrizio Facchinetti, Dave Singh

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Predicting response to benralizumab in patients with COPD: a plain language summary of publication of the GALATHEA and TERRANOVA studies by Gerard J. Criner, Dave Singh, Alberto Papi, Maria Jison, Natalya Makulova, Vivian H. Shih, Laura Brooks, Peter N. Barker, Ubaldo J. Martin

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Diesel exhaust particle exposure in vitro alters monocyte differentiation and function. by Nazia Chaudhuri, Hannah Jary, Simon Lea, Naimat Khan, Katie C Piddock, David H Dockrell, Ken Donaldson, Rodger Duffin, Dave Singh, Lisa C Parker, Ian Sabroe

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Delaying disease progression in COPD with early escalation to triple therapy: a modelling study (DEPICT-2) by Dave Singh, Diego Fabian Litewka, Joan B. Soriano, Adrian Rendon, Frederico Leon Arrabal Fernandes, Rafael Páramo-Arroyo, Tim Trinidad, Hakan Günen, Sudeep Acharya, Bhumika Aggarwal, Gur Levy, Chris Compton, Abdelkader El Hasnaoui, Peter Daley-Yates

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Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD. by Martin A Bewley, Kylie B R Belchamber, Kirandeep K Chana, Richard C Budd, Gavin Donaldson, Jadwiga A Wedzicha, Christopher E Brightling, Iain Kilty, Louise E Donnelly, Peter J Barnes, Dave Singh, Moira K B Whyte, David H Dockrell, COPDMAP

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Genetics of sputum gene expression in chronic obstructive pulmonary disease. by Weiliang Qiu, Michael H Cho, John H Riley, Wayne H Anderson, Dave Singh, Per Bakke, Amund Gulsvik, Augusto A Litonjua, David A Lomas, James D Crapo, Terri H Beaty, Bartolome R Celli, Stephen Rennard, Ruth Tal-Singer, Steven M Fox, Edwin K Silverman, Craig P Hersh, ECLIPSE Investigators

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Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS by Pauline J.M. Kuks, Tessa M. Kole, Monica Kraft, Salman Siddiqui, Leonardo M. Fabbri, Klaus F. Rabe, Alberto Papi, Chris Brightling, Dave Singh, Thys van der Molen, Jan Willem W.H. Kocks, Kian Fan Chung, Ian M. Adcock, Pankaj K. Bhavsar, Nazanin Zounemat Kermani, Irene H. Heijink, Simon D. Pouwels, Huib A.M. Kerstjens, Dirk-Jan Slebos, Maarten van den Berge

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Predictors of treatment REsponse to inhaled corticosteroids (ICS) in Chronic Obstructive pulmonary disease: randomised controlled trials individual participant Data re-Evaluation–p... by Matthew Sperrin, John R Hurst, Michael Miligkos, Joergen Vestbo, Pradeesh Sivapalan, Mike Clarke, Lesley Stewart, Jørgen Vestbo, Dave Singh, Tim Felton, Alexander G Mathioudakis, Rebecca Fortescue, Jennifer Quint, Jonathan Marshall, Anurita Majumdar, Jan Hansel, Alice M Turner, Sinduja Manohar, Catherine Fullwood, Nawar Diar Bakerly, Mark Simmonds, Steven Barnes, Ashley Woodcock, Sebastian Bate, Jens-Ulrik Jensen, Markus Fally, Helen Ashdown, Ashley A Woodcock, Emily Howlett, John Linnell, Alan Preston, Glauco Cappellini, Dmitry Galkin, Olaf Joens

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