Cryo-EM structure of the BLOC-3 complex provides insights into the pathogenesis of Hermansky-Pudlak syndrome by Xin Yong, Guowen Jia, Qin Yang, Chunzhuang Zhou, Sitao Zhang, Huaqing Deng, Daniel D. Billadeau, Zhaoming Su, Da Jia

Get full text

NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation by Elisabeth Hessmann, Jin-San Zhang, Nai-Ming Chen, Marie Hasselluhn, Geou-Yarh Liou, Peter Storz, Volker Ellenrieder, Daniel D. Billadeau, Alexander Koenig

Get full text

CCDC22 mutations that impair COMMD binding cause attenuated 3C/Ritscher-Schinzel syndrome by Amika Singla, Carolyn Rogers, Mary-Joe Touma, Yassin El-Najjar, Alison Colley, Daniel J. Boesch, Daniel D. Billadeau, Jozef Gecz, Baoyu Chen, Ezra Burstein

Get full text

The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness by Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O. Watzlawik, Yin Maggie Chen, Ariel L. Raybuck, Daniel D. Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark R. Boothby, Hu Zeng

Get full text

Fatty acid synthase (FASN) inhibition cooperates with BH3 mimetic drugs to overcome resistance to mitochondrial apoptosis in pancreatic cancer by Travis Vander Steen, Ingrid Espinoza, Cristina Duran, Guillem Casadevall, Eila Serrano-Hervás, Elisabet Cuyàs, Sara Verdura, George Kemble, Scott H. Kaufmann, Robert McWilliams, Sílvia Osuna, Daniel D. Billadeau, Javier A. Menendez, Ruth Lupu

Get full text

Structural basis for Retriever-SNX17 assembly and endosomal sorting by Amika Singla, Daniel J. Boesch, Ho Yee Joyce Fung, Chigozie Ngoka, Avery S. Enriquez, Ran Song, Daniel A. Kramer, Yan Han, Esther Banarer, Andrew Lemoff, Puneet Juneja, Daniel D. Billadeau, Xiaochen Bai, Zhe Chen, Emre E. Turer, Ezra Burstein, Baoyu Chen

Get full text

Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control by Hyoungjun Ham, Jacob B. Hirdler, Daniel T. Bihnam, Zhiming Mao, Joanina K. Gicobi, Bruna Gois Macedo, Maria F. Rodriguez-Quevedo, Destiny F. Schultz, Cristina Correia, Jun Zhong, Kodi E. Martinez, Alma Banuelos, Dallin S. Ashton, Anthony B. Lagnado, Ruifeng Guo, Rodrigo Pessoa, Akhilesh Pandey, Hu Li, Fabrice Lucien, Henrique Borges da Silva, Haidong Dong, Daniel D. Billadeau

Get full text