Chuan He

Chuan He in 2025 Chuan He () is a Chinese-American chemical biologist. He currently serves as the John T. Wilson Distinguished Service Professor at the University of Chicago, and an Investigator of the Howard Hughes Medical Institute. He is best known for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation. He was awarded the 2023 Wolf Prize in Chemistry for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation in addition to his contributions to the invention of TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method that covalently labels 5hmC for its detection and profiling. Provided by Wikipedia
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  1. 1
    Causal role of immunophenotypes in HIV-1 acquisition: insights from Mendelian randomization analysis

    Causal role of immunophenotypes in HIV-1 acquisition: insights from Mendelian randomization analysis by Nan Li, Chuan He

    Published 2025-07-01
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  2. 2
    A study on the spatial dislocation relationship and influencing factors between the ICH and traditional villages in the Xiangjiang River Basin

    A study on the spatial dislocation relationship and influencing factors between the ICH and traditional villages in the Xiangjiang River Basin by Chuan He, lili Chen, Youwang Liang

    Published 2025-07-01
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  3. 3
    Dynamic generalized principal component analysis with applications to fault subspace modeling

    Dynamic generalized principal component analysis with applications to fault subspace modeling by Xiaofeng FENG, Jianfeng XU, Chuan HE

    Published 2022-05-01
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  4. 4
    Analysis of Mechanical Response for a Reinforced Bedded Rock Slope under Rainfall

    Analysis of Mechanical Response for a Reinforced Bedded Rock Slope under Rainfall by Longqi Li, Changlin Li, Chuan He

    Published 2019-01-01
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  5. 5
    Correlation of Maturity Parameters Derived from Methylphenanthrenes and Methyldibenzothiophenes in the Carboniferous Source Rocks from Qaidam Basin, NW China

    Correlation of Maturity Parameters Derived from Methylphenanthrenes and Methyldibenzothiophenes in the Carboniferous Source Rocks from Qaidam Basin, NW China by Chuan He, Haiping Huang, Qianru Wang, Zongxing Li

    Published 2019-01-01
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  6. 6
    pH-dependent Osteoimmunomodulation: Molecular mechanisms and therapeutic targeting in bone disorders

    pH-dependent Osteoimmunomodulation: Molecular mechanisms and therapeutic targeting in bone disorders by Chuanlong Wu, Zujun Sun, Chuan He, Ruixin Sun

    Published 2025-08-01
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  7. 7
    Topology optimization of multi-material acoustic metamaterials for low-frequency and broadband sound absorption

    Topology optimization of multi-material acoustic metamaterials for low-frequency and broadband sound absorption by Feifei Feng, Lei Diao, Chuan He, Meng Tao

    Published 2025-06-01
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  8. 8
    Emergency surgical intervention for bulbar-cervical spinal cord hemorrhage: a case report and review of management strategies

    Emergency surgical intervention for bulbar-cervical spinal cord hemorrhage: a case report and review of management strategies by Chuan He, Qi Zhong, Ying Yang, Gang Cao

    Published 2025-08-01
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  9. 9
    Partially characterized topology guides reliable anchor-free scRNA-integration

    Partially characterized topology guides reliable anchor-free scRNA-integration by Chuan He, Paraskevas Filippidis, Steven H. Kleinstein, Leying Guan

    Published 2025-04-01
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  10. 10
    Comparison of the main pathogenic microorganisms of various common oral diseases in children and adults

    Comparison of the main pathogenic microorganisms of various common oral diseases in children and adults by Siqi Zhou, Tong‐Chuan He, Yuxin Zhang, Hongmei Zhang

    Published 2023-12-01
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  11. 11
    Cognitive Electronic Jamming Decision-Making Method Based on Improved Q-Learning Algorithm

    Cognitive Electronic Jamming Decision-Making Method Based on Improved Q-Learning Algorithm by Huiqin Li, Yanling Li, Chuan He, Jianwei Zhan, Hui Zhang

    Published 2021-01-01
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  12. 12
    Research progress on multisensory stimulation therapy for pain during retinopathy of prematurity screening

    Research progress on multisensory stimulation therapy for pain during retinopathy of prematurity screening by Chunlan Tao, Chuan He, Jinghua Tang, Yongli Li, Yuqin Chen

    Published 2025-08-01
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  13. 13
    Application of biomaterials in cardiac tissue engineering: Current status and prospects

    Application of biomaterials in cardiac tissue engineering: Current status and prospects by Dongshan Zhang, Rui He, Ying Qu, Chuan He, Bingyang Chu

    Published 2024-12-01
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  14. 14
    Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis

    Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis by Chuan He, Saien Lu, Haijie Yu, Yingxian Sun, Xueyao Zhang

    Published 2025-02-01
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  15. 15
    Adaptive opportunistic routing protocol based on forwarding-utility for delay tolerant networks

    Adaptive opportunistic routing protocol based on forwarding-utility for delay tolerant networks by WANG Bo1, HUANG Chuan-he1, YANG Wen-zhong2

    Published 2010-01-01
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  16. 16
    Performance of Slurry Shield Tunnelling in Mixed Strata Based on Field Measurement and Numerical Simulation

    Performance of Slurry Shield Tunnelling in Mixed Strata Based on Field Measurement and Numerical Simulation by Jian Cui, Wang-Hao Xu, Yong Fang, Li-Ming Tao, Chuan He

    Published 2020-01-01
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  17. 17
    Targeting PD-1 post-translational modifications for improving cancer immunotherapy

    Targeting PD-1 post-translational modifications for improving cancer immunotherapy by Jie Shi, Chuan He, Li Chen, Xixin Xing, Wenyi Wei, Jinfang Zhang

    Published 2025-06-01
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  18. 18
    Prototype Experimental Investigation of the Failure Mechanism and Crack Propagation of Segment Lining for Staggered Jointed Assembly

    Prototype Experimental Investigation of the Failure Mechanism and Crack Propagation of Segment Lining for Staggered Jointed Assembly by Songyu Cao, Kun Feng, Xun Liu, Mingqing Xiao, Chuan He, Ce Li

    Published 2020-01-01
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  19. 19
    A Privacy-Preserving Polymorphic Heterogeneous Security Architecture for Cloud–Edge Collaboration Industrial Control Systems

    A Privacy-Preserving Polymorphic Heterogeneous Security Architecture for Cloud–Edge Collaboration Industrial Control Systems by Yukun Niu, Xiaopeng Han, Chuan He, Yunfan Wang, Zhigang Cao, Ding Zhou

    Published 2025-07-01
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  20. 20
    Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study

    Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study by Yinyan Li, Chuan He, Haijie Yu, Di Wu, Li Liu, Xueyao Zhang

    Published 2025-04-01
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