Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs by Frank Wessely, Martin Bartl, Reinhard Guthke, Pu Li, Stefan Schuster, Christoph Kaleta

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Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis. by Jan Ewald, Flora Rivieccio, Lukáš Radosa, Stefan Schuster, Axel A Brakhage, Christoph Kaleta

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Genome-scale metabolic modelling reveals interactions and key roles of symbiont clades in a sponge holobiont by Shan Zhang, Weizhi Song, Geogios Marinos, Silvio Waschina, Johannes Zimmermann, Christoph Kaleta, Torsten Thomas

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Metabolic modelling reveals increased autonomy and antagonism in type 2 diabetic gut microbiota by A Samer Kadibalban, Axel Künstner, Torsten Schröder, Julius Zauleck, Oliver Witt, Georgios Marinos, Christoph Kaleta

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Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice by Felix Sommer, Joana P. Bernardes, Lena Best, Nina Sommer, Jacob Hamm, Berith Messner, Víctor A. López-Agudelo, Antonella Fazio, Georgios Marinos, A. Samer Kadibalban, Go Ito, Maren Falk-Paulsen, Christoph Kaleta, Philip Rosenstiel

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Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis by Lea Järke, Saskia Weber‐Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen, Christoph Röcken, Andreas Tholey, Christoph Kaleta, Jan Rupp, Philip Rosenstiel, Felix Sommer

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Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs against RNA viruses by Alina Renz, Mirjam Hohner, Raphaël Jami, Maximilian Breitenbach, Jonathan Josephs-Spaulding, Johanna Dürrwald, Lena Best, Victoria Dulière, Chloé Mialon, Stefanie M. Bader, Georgios Marinos, Nantia Leonidou, Filipe Cabreiro, Marc Pellegrini, Marcel Doerflinger, Manuel Rosa-Calatrava, Andrés Pizzorno, Andreas Dräger, Michael Schindler, Christoph Kaleta

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Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans by Lena Peters, Moritz Drechsler, Michael A. Herrera, Jing Liu, Barbara Pees, Johanna Jarstorff, Anna Czerwinski, Francesca Lubbock, Georgia Angelidou, Liesa Salzer, Karlis Arturs Moors, Nicole Paczia, Yi-Ming Shi, Hinrich Schulenburg, Christoph Kaleta, Michael Witting, Manuel Liebeke, Dominic J. Campopiano, Helge B. Bode, Katja Dierking

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A dietary carbohydrate – gut Parasutterella – human fatty acid biosynthesis metabolic axis in obesity and type 2 diabetes by Lea Henneke, Kristina Schlicht, Nadia A. Andreani, Tim Hollstein, Tobias Demetrowitsch, Carina Knappe, Katharina Hartmann, Julia Jensen-Kroll, Nathalie Rohmann, Daniela Pohlschneider, Corinna Geisler, Dominik M. Schulte, Ute Settgast, Kathrin Türk, Johannes Zimmermann, Christoph Kaleta, John F. Baines, Jane Shearer, Shrushti Shah, Grace Shen-Tu, Karin Schwarz, Andre Franke, Stefan Schreiber, Matthias Laudes

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