Personalized (N-of-1) Trials for Patient-Centered Treatments of Multimorbidity by Jerry Suls, Catherine Alfano, Christina Yap

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Naturopathic approaches to irritable bowel syndrome: protocol for a prospective observational study in academic teaching clinics by Joshua Z. Goldenberg, Amie Steel, Andrew Day, Christina Yap, Ryan Bradley, Kieran Cooley

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Exploring the barriers to, and importance of, participant diversity in early-phase clinical trials: an interview-based qualitative study of professionals and patient and public rep... by Cindy Cooper, Katie Biggs, Alexander Rothman, Christina Yap, Fiona Thistlethwaite, Della Ogunleye, Munyaradzi Dimairo, Robin Chatters, Shamila Ditta, Jonathan Woodward

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Interpreting results from biomarker-guided clinical trials: avoiding “negative” or “failed” terminology by Nurulamin M. Noor, Haiyan Zheng, David S. Robertson, Joshua Savage, Christina Yap, Andrea L. Jorgensen, James M. S. Wason, on behalf of the MRC-NIHR Trial Methodology Research Partnership (TMRP) Precision Medicine Working Group

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Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: t... by Martin Forster, Joseph Sacco, Christina Yap, Kevin Harrington, Hisham Mehanna, Anthony Kong, James Good, Amanda Kirkham, Joshua Savage, Rhys Mant, Laura Llewellyn, Joanna Parish, Rachel Spruce, Stefano Schipani, Patrick Murray, Gary Middleton

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Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome. by Brian V Tsu, Rimjhim Agarwal, Nandan S Gokhale, Jessie Kulsuptrakul, Andrew P Ryan, Elizabeth J Fay, Lennice K Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A Turcotte, Sofia E Delgado-Rodriguez, Russell E Vance, Jennifer L Hyde, Ram Savan, Patrick S Mitchell, Matthew D Daugherty

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Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies by Julia Lederhofer, Andrew J. Borst, Lam Nguyen, Rebecca A. Gillespie, Connor J. Williams, Emma L. Walker, Julie E. Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon-Xhi Tan, Thi H. T. Do, Michelle Ravichandran, Adrian B. McDermott, Valerie Le Sage, Sarah F. Andrews, Barney S. Graham, Adam K. Wheatley, Douglas S. Reed, Neil P. King, Masaru Kanekiyo

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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