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Obesity and Multiple Sclerosis: A Mendelian Randomization Study. by Lauren E Mokry, Stephanie Ross, Nicholas J Timpson, Stephen Sawcer, George Davey Smith, J Brent Richards
Published 2016-06-01Get full text
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Identifying key physiological and clinical factors for traumatic brain injury patient management using network analysis and machine learning by Hasitha Kuruwita Arachchige, Shu Kay Ng, Alan Wee-Chung Liew, Brent Richards, Luke Haseler, Kuldeep Kumar, Kelvin Ross, Ping Zhang
Published 2025-01-01Get full text
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Identifying key physiological and clinical factors for traumatic brain injury patient management using network analysis and machine learning. by Hasitha Kuruwita Arachchige, Shu Kay Ng, Alan Wee-Chung Liew, Brent Richards, Luke Haseler, Kuldeep Kumar, Kelvin Ross, Ping Zhang
Published 2025-01-01Get full text
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Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation by Marjorie Labrecque, Elsa Brunet-Ratnasingham, Laura K. Hamilton, Daniel Auld, Alexandre Montpetit, Brent Richards, Madeleine Durand, Simon Rousseau, Andrés Finzi, Daniel E. Kaufmann, Martine Tetreault
Published 2025-04-01Get full text
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Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study. by Despoina Manousaki, Lavinia Paternoster, Marie Standl, Miriam F Moffatt, Martin Farrall, Emmanuelle Bouzigon, David P Strachan, Florence Demenais, Mark Lathrop, William O C M Cookson, J Brent Richards
Published 2017-05-01Get full text
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Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study. by Guillaume Butler-Laporte, Tomoko Nakanishi, Vincent Mooser, David R Morrison, Tala Abdullah, Olumide Adeleye, Noor Mamlouk, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Annarita Giliberti, Alessandra Renieri, Yiheng Chen, Sirui Zhou, Vincenzo Forgetta, J Brent Richards
Published 2021-06-01Get full text
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The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study. by Aaron Leong, Waheed Rehman, Zari Dastani, Celia Greenwood, Nicholas Timpson, Lisa Langsetmo, Claudie Berger, METASTROKE, Lei Fu, Betty Y L Wong, Suneil Malik, Rainer Malik, David A Hanley, David E C Cole, David Goltzman, J Brent Richards
Published 2014-10-01Get full text
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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... by Andrew R Wood, John R B Perry, Toshiko Tanaka, Dena G Hernandez, Hou-Feng Zheng, David Melzer, J Raphael Gibbs, Michael A Nalls, Michael N Weedon, Tim D Spector, J Brent Richards, Stefania Bandinelli, Luigi Ferrucci, Andrew B Singleton, Timothy M Frayling
Published 2013-01-01Get full text
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The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. by Josine L Min, Jennifer M Taylor, J Brent Richards, Tim Watts, Fredrik H Pettersson, John Broxholme, Kourosh R Ahmadi, Gabriela L Surdulescu, Ernesto Lowy, Christian Gieger, Chris Newton-Cheh, Markus Perola, Nicole Soranzo, Ida Surakka, Cecilia M Lindgren, Jiannis Ragoussis, Andrew P Morris, Lon R Cardon, Tim D Spector, Krina T Zondervan
Published 2011-01-01Get full text
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Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study. by Vincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P Kemp, Maria Nethander, Daniel Evans, John A Morris, Douglas P Kiel, Fernando Rivadeneira, Helena Johansson, Nicholas C Harvey, Dan Mellström, Magnus Karlsson, Cyrus Cooper, David M Evans, Robert Clarke, John A Kanis, Eric Orwoll, Eugene V McCloskey, Claes Ohlsson, Joelle Pineau, William D Leslie, Celia M T Greenwood, J Brent Richards
Published 2020-07-01Get full text
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Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. by Carolina Medina-Gomez, John P Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M Evans, Denise H M Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, M Carola Zillikens, Ole K Olstad, Hou-Feng Zheng, J Brent Richards, Beate St Pourcain, Albert Hofman, Vincent W V Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M Gautvik, André G Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H Tobias, Fernando Rivadeneira
Published 2012-07-01Get full text
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An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. by Yi-Hsiang Hsu, M Carola Zillikens, Scott G Wilson, Charles R Farber, Serkalem Demissie, Nicole Soranzo, Estelle N Bianchi, Elin Grundberg, Liming Liang, J Brent Richards, Karol Estrada, Yanhua Zhou, Atila van Nas, Miriam F Moffatt, Guangju Zhai, Albert Hofman, Joyce B van Meurs, Huibert A P Pols, Roger I Price, Olle Nilsson, Tomi Pastinen, L Adrienne Cupples, Aldons J Lusis, Eric E Schadt, Serge Ferrari, André G Uitterlinden, Fernando Rivadeneira, Timothy D Spector, David Karasik, Douglas P Kiel
Published 2010-06-01Get full text
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Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. by Rui Li, Felix F Brockschmidt, Amy K Kiefer, Hreinn Stefansson, Dale R Nyholt, Kijoung Song, Sita H Vermeulen, Stavroula Kanoni, Daniel Glass, Sarah E Medland, Maria Dimitriou, Dawn Waterworth, Joyce Y Tung, Frank Geller, Stefanie Heilmann, Axel M Hillmer, Veronique Bataille, Sibylle Eigelshoven, Sandra Hanneken, Susanne Moebus, Christine Herold, Martin den Heijer, Grant W Montgomery, Panos Deloukas, Nicholas Eriksson, Andrew C Heath, Tim Becker, Patrick Sulem, Massimo Mangino, Peter Vollenweider, Tim D Spector, George Dedoussis, Nicholas G Martin, Lambertus A Kiemeney, Vincent Mooser, Kari Stefansson, David A Hinds, Markus M Nöthen, J Brent Richards
Published 2012-05-01Get full text
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Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. by Nicole Soranzo, Fernando Rivadeneira, Usha Chinappen-Horsley, Ida Malkina, J Brent Richards, Naomi Hammond, Lisette Stolk, Alexandra Nica, Michael Inouye, Albert Hofman, Jonathan Stephens, Eleanor Wheeler, Pascal Arp, Rhian Gwilliam, P Mila Jhamai, Simon Potter, Amy Chaney, Mohammed J R Ghori, Radhi Ravindrarajah, Sergey Ermakov, Karol Estrada, Huibert A P Pols, Frances M Williams, Wendy L McArdle, Joyce B van Meurs, Ruth J F Loos, Emmanouil T Dermitzakis, Kourosh R Ahmadi, Deborah J Hart, Willem H Ouwehand, Nicholas J Wareham, Inês Barroso, Manjinder S Sandhu, David P Strachan, Gregory Livshits, Timothy D Spector, André G Uitterlinden, Panos Deloukas
Published 2009-04-01Get full text
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Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. by Emma L Duncan, Patrick Danoy, John P Kemp, Paul J Leo, Eugene McCloskey, Geoffrey C Nicholson, Richard Eastell, Richard L Prince, John A Eisman, Graeme Jones, Philip N Sambrook, Ian R Reid, Elaine M Dennison, John Wark, J Brent Richards, Andre G Uitterlinden, Tim D Spector, Chris Esapa, Roger D Cox, Steve D M Brown, Rajesh V Thakker, Kathryn A Addison, Linda A Bradbury, Jacqueline R Center, Cyrus Cooper, Catherine Cremin, Karol Estrada, Dieter Felsenberg, Claus-C Glüer, Johanna Hadler, Margaret J Henry, Albert Hofman, Mark A Kotowicz, Joanna Makovey, Sing C Nguyen, Tuan V Nguyen, Julie A Pasco, Karena Pryce, David M Reid, Fernando Rivadeneira, Christian Roux, Kari Stefansson, Unnur Styrkarsdottir, Gudmar Thorleifsson, Rumbidzai Tichawangana, David M Evans, Matthew A Brown
Published 2011-04-01Get full text
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