Antonio Vidal-Puig

Antonio Vidal-Puig, Spanish scientist Antonio Vidal-Puig (born Valencia, Spain June 12, 1962) is a Spanish medical doctor and scientist who works as a Professor of Molecular Nutrition and Metabolism at the University of Cambridge (UK), best known for advancing the concept that pharmacological targeting of brown fat may serve to treat overweight and obesity in affected individuals, as well as for introducing the concept of adipose tissue "expandability" as an important factor in the pathogenesis of insulin resistance in the context of positive energy balance. His published work focuses on areas such as adipose tissue metabolism and lipotoxicity, regulation of insulin secretion,  and the pathophysiology of metabolic syndrome, obesity, and type 2 diabetes. In April 2024, he was granted the rank of ''doctor honoris causa'' from the King Juan Carlos University, Madrid. Provided by Wikipedia
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  1. 1
    Nothing Iffy about HIF in the Hypothalamus.

    Nothing Iffy about HIF in the Hypothalamus. by Sam Virtue, Antonio Vidal-Puig

    Published 2011-07-01
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  2. 2
    It's not how fat you are, it's what you do with it that counts.

    It's not how fat you are, it's what you do with it that counts. by Samuel Virtue, Antonio Vidal-Puig

    Published 2008-09-01
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  3. 3
    Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes.

    Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes. by Sergio Rodriguez-Cuenca, Lauren Whyte, Rachel Hagen, Antonio Vidal-Puig, Maria Fuller

    Published 2016-01-01
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  4. 4
    Genome-wide profiling of microRNAs in adipose mesenchymal stem cell differentiation and mouse models of obesity.

    Genome-wide profiling of microRNAs in adipose mesenchymal stem cell differentiation and mouse models of obesity. by Lena Bengestrate, Sam Virtue, Mark Campbell, Antonio Vidal-Puig, Dirk Hadaschik, Peter Hahn, Wolfgang Bielke

    Published 2011-01-01
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  5. 5
    Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation.

    Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. by Johan Fernø, Luis Varela, Silje Skrede, María Jesús Vázquez, Rubén Nogueiras, Carlos Diéguez, Antonio Vidal-Puig, Vidar M Steen, Miguel López

    Published 2011-01-01
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  6. 6
    Distinct signalling dynamics of BMP4 and BMP9 in brown versus white adipocytes

    Distinct signalling dynamics of BMP4 and BMP9 in brown versus white adipocytes by Benjamin Constant, Ioannis Kamzolas, Xudong Yang, Jingxu Guo, Sonia Rodriguez-Fdez, Iman Mali, Sergio Rodriguez-Cuenca, Evangelia Petsalaki, Antonio Vidal-Puig, Wei Li

    Published 2025-05-01
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  7. 7
    Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.

    Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta. by Marc Liesa, Bárbara Borda-d'Agua, Gema Medina-Gómez, Christopher J Lelliott, José Carlos Paz, Manuel Rojo, Manuel Palacín, Antonio Vidal-Puig, Antonio Zorzano

    Published 2008-01-01
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  8. 8
    Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.

    Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. by Matthew Van De Pette, Simon J Tunster, Grainne I McNamara, Tatyana Shelkovnikova, Steven Millership, Lindsay Benson, Stuart Peirson, Mark Christian, Antonio Vidal-Puig, Rosalind M John

    Published 2016-03-01
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  9. 9
    PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

    PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. by Gema Medina-Gomez, Sarah L Gray, Laxman Yetukuri, Kenju Shimomura, Sam Virtue, Mark Campbell, R Keira Curtis, Mercedes Jimenez-Linan, Margaret Blount, Giles S H Yeo, Miguel Lopez, Tuulikki Seppänen-Laakso, Frances M Ashcroft, Matej Oresic, Antonio Vidal-Puig

    Published 2007-04-01
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  10. 10
    Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo.

    Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo. by Sam Virtue, Mojgan Masoodi, Vidya Velagapudi, Chong Yew Tan, Martin Dale, Tapani Suorti, Marc Slawik, Margaret Blount, Keith Burling, Mark Campbell, Naomi Eguchi, Gema Medina-Gomez, Jaswinder K Sethi, Matej Orešič, Yoshihiro Urade, Julian L Griffin, Antonio Vidal-Puig

    Published 2012-01-01
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  11. 11
    Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food.

    Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. by Laura Dearden, Isadora C Furigo, Lucas C Pantaleão, L W P Wong, Denise S Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A Kentistou, Maria V Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K Ong, John R B Perry, Jose Donato, Susan E Ozanne

    Published 2024-06-01
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  12. 12
    Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans.

    Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans. by Kirsi H Pietiläinen, Tomasz Róg, Tuulikki Seppänen-Laakso, Sam Virtue, Peddinti Gopalacharyulu, Jing Tang, Sergio Rodriguez-Cuenca, Arkadiusz Maciejewski, Jussi Naukkarinen, Anna-Liisa Ruskeepää, Perttu S Niemelä, Laxman Yetukuri, Chong Yew Tan, Vidya Velagapudi, Sandra Castillo, Heli Nygren, Tuulia Hyötyläinen, Aila Rissanen, Jaakko Kaprio, Hannele Yki-Järvinen, Ilpo Vattulainen, Antonio Vidal-Puig, Matej Orešič

    Published 2011-06-01
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  13. 13
    A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

    A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. by David B Savage, Lanmin Zhai, Balasubramanian Ravikumar, Cheol Soo Choi, Johanna E Snaar, Amanda C McGuire, Sung-Eun Wou, Gemma Medina-Gomez, Sheene Kim, Cheryl B Bock, Dyann M Segvich, Bhavana Solanky, Dinesh Deelchand, Antonio Vidal-Puig, Nicholas J Wareham, Gerald I Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A Pederson, Peter J Roach, Stephen O'Rahilly, Anna A DePaoli-Roach

    Published 2008-01-01
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  14. 14
    Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice

    Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice by Cheukyau Luk, Katherine I. Bridge, Nele Warmke, Katie J. Simmons, Michael Drozd, Amy Moran, Amanda D. V. MacCannell, Chew W. Cheng, Sam Straw, Jason L. Scragg, Jessica Smith, Claire H. Ozber, Chloe G. Wilkinson, Anna Skromna, Natallia Makava, Hiran A. Prag, T. Simon Futers, Oliver I. Brown, Alexander-Francisco Bruns, Andrew MN Walker, Nicole T. Watt, Romana Mughal, Kathryn J. Griffin, Nadira Y. Yuldasheva, Sunti Limumpornpetch, Hema Viswambharan, Piruthivi Sukumar, David J. Beech, Antonio Vidal-Puig, Klaus K. Witte, Michael P. Murphy, Richard C. Hartley, Stephen B. Wheatcroft, Richard M. Cubbon, Lee D. Roberts, Mark T. Kearney, Natalie J. Haywood

    Published 2025-01-01
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