Editorial: Tumor-associated tertiary lymphoid structures response during immunotherapy by Ileana Soto Mauldin, Christine Mall Minnar, Antoine Italiano, Antoine Italiano

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Immune-induced thrombocytopenia by pembrolizumab: case report and review of literature by Nathan El-Ghazzi, Anna Monier, Antoine Italiano, Aude Besson, Eurydice Angeli

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Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction by Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

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Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas by Jean Philippe Guegan, Nathan El Ghazzi, Julien Vibert, Christophe Rey, Lucile Vanhersecke, Jean Michel Coindre, Maud Toulmonde, Mariella Spalato Ceruso, Florent Peyraud, Alban Bessede, Antoine Italiano

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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab by Maud Toulmonde, Jean-Philippe Guégan, Mariella Spalato-Ceruso, Thibaud Valentin, Rastilav Bahleda, Florent Peyraud, Christophe Rey, Michèle Kind, Coralie Cantarel, Carine Bellera, Lucile Vanhersecke, Alban Bessede, Antoine Italiano

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Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers. by Paolo Puccetti, Francesca Fallarino, Antoine Italiano, Isabelle Soubeyran, Gaetan MacGrogan, Marc Debled, Valerie Velasco, Dominique Bodet, Sandrine Eimer, Marc Veldhoen, Georges C Prendergast, Michael Platten, Alban Bessede, Gilles J Guillemin

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First-in-human phase 1 study of the ICOS agonist feladilimab on patients with advanced solid tumors by David Turner, Antoine Italiano, Victor Moreno, Steven Hirschfeld, Juan Martin-Liberal, Michele Maio, Todd M Bauer, Christophe Le Tourneau, Danny Rischin, Catherine Ellis, Eric Angevin, Aaron Hansen, Helen Zhou, Ivan Diaz-Padilla, Frans Opdam, Sapna Yadavilli, Marc Ballas

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Personalized Therapy in a Patient With EGFR-Mutated NSCLC Developing Sequential CCDC6-RET Fusion and BRAF V600E Mutation as Bypass Resistance Mechanisms by Arianna Marinello, MD, Claudia Parisi, MD, Damien Vasseur, PhD, David Combarel, PharmD, Juliette Bihoreau, NP, Pernelle Lavaud, MD, Rémy Ezzedine, MD, Lodovica Zullo, MD, Luc Friboulet, PhD, Gerard Zalcman, MD, PhD, Antoine Italiano, MD, PhD, Benjamin Besse, MD, PhD, Mihaela Aldea, MD, PhD

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Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study by Emmanuelle Bompas, Loïc Campion, Antoine Italiano, Axel Le Cesne, Christine Chevreau, Nicolas Isambert, Maud Toulmonde, Olivier Mir, Isabelle Ray‐Coquard, Sophie Piperno‐Neumann, Esma Saada‐Bouzid, Maria Rios, Jean‐Emmanuel Kurtz, Corinne Delcambre, Pascale Dubray‐Longeras, Florence Duffaud, Marie Karanian, François Le Loarer, Patrick Soulié, Nicolas Penel, Jean‐Yves Blay

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Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference by Pierre-Antoine Laurent, Fabrice André, Alexandre Bobard, Desiree Deandreis, Sandra Demaria, Stephane Depil, Stefan B. Eichmüller, Cristian Fernandez-Palomo, Floris Foijer, Lorenzo Galluzzi, Jérôme Galon, Matthias Guckenberger, Kevin J. Harrington, Fernanda G. Herrera, Peter E. Huber, Antoine Italiano, Sana D. Karam, Guido Kroemer, Philippe Lambin, Carola Leuschner, Alberto Mantovani, Etienne Meylan, Michele Mondini, Mikael J. Pittet, Jean-Pierre Pouget, Jordi Remon, Claus S. Sørensen, Christos Sotiriou, Claire Vanpouille-Box, Ralph R. Weichselbaum, James W. Welsh, Laurence Zitvogel, Silvia C. Formenti, Eric Deutsch

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