Identifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine. by Angus G Jones, Beverley M Shields, Christopher J Hyde, William E Henley, Andrew T Hattersley

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Two cases of neonatal hyperglycemia caused by a homozygous COQ9 stop‐gain variant by Russell Donis, Maryam Al Badi, Nadia Alhashmi, Andrew T Hattersley, Sarah E Flanagan, Elisa De Franco

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Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c? by Angus G Jones, Mike Lonergan, William E Henley, Ewan R Pearson, Andrew T Hattersley, Beverley M Shields

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Gain-of-function mutations in the K(ATP) channel (KCNJ11) impair coordinated hand-eye tracking. by James S McTaggart, Ned Jenkinson, John-Stuart Brittain, Siri A W Greeley, Andrew T Hattersley, Frances M Ashcroft

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Use of HbA1c in the identification of patients with hyperglycaemia caused by a glucokinase mutation: observational case control studies. by Anna M Steele, Kirsty J Wensley, Sian Ellard, Rinki Murphy, Maggie Shepherd, Kevin Colclough, Andrew T Hattersley, Beverley M Shields

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Waist circumference and glycaemia are strong predictors of progression to diabetes in individuals with prediabetes in sub-Saharan Africa: 4-year prospective cohort study in Malawi. by Wisdom P Nakanga, Amelia C Crampin, Joseph Mkandawire, Louis Banda, Rob C Andrews, Andrew T Hattersley, Moffat J Nyirenda, Lauren R Rodgers

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Infancy‐onset diabetes caused by de‐regulated AMPylation of the human endoplasmic reticulum chaperone BiP by Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco

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Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable. by Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, George Davey Smith

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Dietary energy density affects fat mass in early adolescence and is not modified by FTO variants. by Laura Johnson, Cornelia H M van Jaarsveld, Pauline M Emmett, Imogen S Rogers, Andy R Ness, Andrew T Hattersley, Nicholas J Timpson, George Davey Smith, Susan A Jebb

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Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis. by William D Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N Beaumont, Bridget A Knight, Andrew R Wood, Susan M Ring, Andrew T Hattersley, Rachel M Freathy, Debbie A Lawlor

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. by Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling

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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies. by Robin N Beaumont, Sarah J Kotecha, Andrew R Wood, Bridget A Knight, Sylvain Sebert, Mark I McCarthy, Andrew T Hattersley, Marjo-Riitta Järvelin, Nicholas J Timpson, Rachel M Freathy, Sailesh Kotecha

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Patterns of postmeal insulin secretion in individuals with sulfonylurea-treated KCNJ11 neonatal diabetes show predominance of non-KATP-channel pathways by Pamela Bowman, Timothy J McDonald, Bridget A Knight, Sarah E Flanagan, Maria Leveridge, Steve R Spaull, Beverley M Shields, Suzanne Hammersley, Maggie H Shepherd, Robert C Andrews, Kashyap A Patel, Andrew T Hattersley

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Complete loss of PAX4 causes transient neonatal diabetes in humans by James Russ-Silsby, Yunkyeong Lee, Varsha Rajesh, Mahsa Amoli, Nasser Ali Mirhosseini, Tushar Godbole, Matthew B. Johnson, D. Evelyn Ibarra, Han Sun, Nicole A.J. Krentz, Matthew N. Wakeling, Sarah E. Flanagan, Andrew T. Hattersley, Anna L. Gloyn, Elisa De Franco

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tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans. by Mariana Igoillo-Esteve, Anne Genin, Nelle Lambert, Julie Désir, Isabelle Pirson, Baroj Abdulkarim, Nicolas Simonis, Anais Drielsma, Lorella Marselli, Piero Marchetti, Pierre Vanderhaeghen, Décio L Eizirik, Wim Wuyts, Cécile Julier, Ali J Chakera, Sian Ellard, Andrew T Hattersley, Marc Abramowicz, Miriam Cnop

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Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children. by Ezio Bonifacio, Andreas Beyerlein, Markus Hippich, Christiane Winkler, Kendra Vehik, Michael N Weedon, Michael Laimighofer, Andrew T Hattersley, Jan Krumsiek, Brigitte I Frohnert, Andrea K Steck, William A Hagopian, Jeffrey P Krischer, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Beena Akolkar, Richard A Oram, Stephen S Rich, Anette-G Ziegler, TEDDY Study Group

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Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant. by Colin N A Palmer, Cristina Maglio, Carlo Pirazzi, Maria Antonella Burza, Martin Adiels, Lindsay Burch, Louise A Donnelly, Helen Colhoun, Alexander S Doney, John F Dillon, Ewan R Pearson, Mark McCarthy, Andrew T Hattersley, Tim Frayling, Andrew D Morris, Markku Peltonen, Per-Arne Svensson, Peter Jacobson, Jan Borén, Lars Sjöström, Lena M S Carlsson, Stefano Romeo

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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. by Christopher G Bell, Sarah Finer, Cecilia M Lindgren, Gareth A Wilson, Vardhman K Rakyan, Andrew E Teschendorff, Pelin Akan, Elia Stupka, Thomas A Down, Inga Prokopenko, Ian M Morison, Jonathan Mill, Ruth Pidsley, International Type 2 Diabetes 1q Consortium, Panos Deloukas, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Stephan Beck, Graham A Hitman

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Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling by Katherine A. Kentistou, Brandon E. M. Lim, Lena R. Kaisinger, Valgerdur Steinthorsdottir, Luke N. Sharp, Kashyap A. Patel, Vinicius Tragante, Gareth Hawkes, Eugene J. Gardner, Thorhildur Olafsdottir, Andrew R. Wood, Yajie Zhao, Gudmar Thorleifsson, Felix R. Day, Susan E. Ozanne, Andrew T. Hattersley, Stephen O’Rahilly, Kari Stefansson, Ken K. Ong, Robin N. Beaumont, John R. B. Perry, Rachel M. Freathy

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Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study. by Richard Howey, Jonathan Adam, Jerzy Adamski, Natalie N Atabaki, Søren Brunak, Piotr Jaroslaw Chmura, Federico De Masi, Emmanouil T Dermitzakis, Juan J Fernandez-Tajes, Ian M Forgie, Paul W Franks, Giuseppe N Giordano, Mark Haid, Torben Hansen, Tue H Hansen, Peter P Harms, Andrew T Hattersley, Mun-Gwan Hong, Ulrik Plesner Jacobsen, Angus G Jones, Robert W Koivula, Tarja Kokkola, Anubha Mahajan, Andrea Mari, Mark I McCarthy, Timothy J McDonald, Petra B Musholt, Imre Pavo, Ewan R Pearson, Oluf Pedersen, Hartmut Ruetten, Femke Rutters, Jochen M Schwenk, Sapna Sharma, Leen M 't Hart, Henrik Vestergaard, Mark Walker, IMI DIRECT Consortium, Ana Viñuela, Heather J Cordell

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