Leveraging Interoperable Electronic Health Record (EHR) Data for Distributed Analyses in Clinical Research: Technical Implementation Report of the HELP Study by Julia Palm, Kutaiba Saleh, André Scherag, Danny Ammon

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One-sample missing DNA-methylation value imputation by Christelle Kemda Ngueda, Julia Palm, Flavia Remo, André Scherag, Lutz Leistritz

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Internet-based cognitive-behavioural writing therapy for reducing post-traumatic stress after severe sepsis in patients and their spouses (REPAIR): results of a randomised-controll... by André Scherag, Jenny Rosendahl, Christine Knaevelsrud, Helen Niemeyer, Miriam Kesselmeier, Romina Gawlytta, Maria Böttche

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Challenges in detecting and predicting adverse drug events via distributed analysis of electronic health record data from German university hospitals by Anna Maria Wermund, Torsten Thalheim, André Medek, Florian Schmidt, Thomas Peschel, Alexander Strübing, Daniel Neumann, André Scherag, Markus Loeffler, Miriam Kesselmeier, Ulrich Jaehde

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Challenges in detecting and predicting adverse drug events via distributed analysis of electronic health record data from German university hospitals. by Anna Maria Wermund, Torsten Thalheim, André Medek, Florian Schmidt, Thomas Peschel, Alexander Strübing, Daniel Neumann, André Scherag, Markus Loeffler, Miriam Kesselmeier, Ulrich Jaehde, POLAR_MI Consortium

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Automated sample annotation for diabetes mellitus in healthcare integrated biobanking by Johannes Stolp, Christoph Weber, Danny Ammon, André Scherag, Claudia Fischer, Christof Kloos, Gunter Wolf, P. Christian Schulze, Utz Settmacher, Michael Bauer, Andreas Stallmach, Michael Kiehntopf, Boris Betz

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The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. by Helen N Lyon, Valur Emilsson, Anke Hinney, Iris M Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, G Bragi Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy Trang Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A Raby, Edwin K Silverman, Scott T Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L Butler, Richard S Cooper, Caroline S Fox, Christopher J O'Donnell, Caren Vollmert, Juan C Celedón, H Erich Wichmann, Johannes Hebebrand, Kari Stefansson, Christoph Lange, Joel N Hirschhorn

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Leveraging electronic medical records to evaluate a computerized decision support system for staphylococcus bacteremia by Julia Palm, Ssuhir Alaid, Danny Ammon, Julian Brandes, Andreas Dürschmid, Claudia Fischer, Jonas Fortmann, Kristin Friebel, Sarah Geihs, Anne-Kathrin Hartig, Donghui He, Andrew J. Heidel, Petra Hetfeld, Roland Ihle, Suzanne Kahle, Verena Koi, Margarethe Konik, Frauke Kretzschmann, Henner Kruse, Norman Lippmann, Christoph Lübbert, Gernot Marx, Rafael Mikolajczyk, Anne Mlocek, Stefan Moritz, Christoph Müller, Susanne Müller, Ariadna Pérez Garriga, Lo An Phan-Vogtmann, Diana Pietzner, Mathias W. Pletz, Mario Popp, Maike Rebenstorff, Jonas Renz, Florian Rißner, Rainer Röhrig, Kutaiba Saleh, Sebastian G. Schönherr, Cord Spreckelsen, Anja Stempel, Abel Stolz, Eric Thomas, Susanne Thon, Daniel Tiller, Sebastian Uschmann, Sebastian Wendt, Thomas Wendt, Philipp Winnekens, Oliver Witzke, Stefan Hagel, André Scherag

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Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. by André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre

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Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. by Clive J Hoggart, Giulia Venturini, Massimo Mangino, Felicia Gomez, Giulia Ascari, Jing Hua Zhao, Alexander Teumer, Thomas W Winkler, Natalia Tšernikova, Jian'an Luan, Evelin Mihailov, Georg B Ehret, Weihua Zhang, David Lamparter, Tõnu Esko, Aurelien Macé, Sina Rüeger, Pierre-Yves Bochud, Matteo Barcella, Yves Dauvilliers, Beben Benyamin, David M Evans, Caroline Hayward, Mary F Lopez, Lude Franke, Alessia Russo, Iris M Heid, Erika Salvi, Sailaja Vendantam, Dan E Arking, Eric Boerwinkle, John C Chambers, Giovanni Fiorito, Harald Grallert, Simonetta Guarrera, Georg Homuth, Jennifer E Huffman, David Porteous, Generation Scotland Consortium, LifeLines Cohort study, GIANT Consortium, Darius Moradpour, Alex Iranzo, Johannes Hebebrand, John P Kemp, Gert J Lammers, Vincent Aubert, Markus H Heim, Nicholas G Martin, Grant W Montgomery, Rosa Peraita-Adrados, Joan Santamaria, Francesco Negro, Carsten O Schmidt, Robert A Scott, Tim D Spector, Konstantin Strauch, Henry Völzke, Nicholas J Wareham, Wei Yuan, Jordana T Bell, Aravinda Chakravarti, Jaspal S Kooner, Annette Peters, Giuseppe Matullo, Henri Wallaschofski, John B Whitfield, Fred Paccaud, Peter Vollenweider, Sven Bergmann, Jacques S Beckmann, Mehdi Tafti, Nicholas D Hastie, Daniele Cusi, Murielle Bochud, Timothy M Frayling, Andres Metspalu, Marjo-Riitta Jarvelin, André Scherag, George Davey Smith, Ingrid B Borecki, Valentin Rousson, Joel N Hirschhorn, Carlo Rivolta, Ruth J F Loos, Zoltán Kutalik

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Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. by Joshua C Randall, Thomas W Winkler, Zoltán Kutalik, Sonja I Berndt, Anne U Jackson, Keri L Monda, Tuomas O Kilpeläinen, Tõnu Esko, Reedik Mägi, Shengxu Li, Tsegaselassie Workalemahu, Mary F Feitosa, Damien C Croteau-Chonka, Felix R Day, Tove Fall, Teresa Ferreira, Stefan Gustafsson, Adam E Locke, Iain Mathieson, Andre Scherag, Sailaja Vedantam, Andrew R Wood, Liming Liang, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Emmanouil T Dermitzakis, Antigone S Dimas, Fredrik Karpe, Josine L Min, George Nicholson, Deborah J Clegg, Thomas Person, Jon P Krohn, Sabrina Bauer, Christa Buechler, Kristina Eisinger, DIAGRAM Consortium, Amélie Bonnefond, Philippe Froguel, MAGIC Investigators, Jouke-Jan Hottenga, Inga Prokopenko, Lindsay L Waite, Tamara B Harris, Albert Vernon Smith, Alan R Shuldiner, Wendy L McArdle, Mark J Caulfield, Patricia B Munroe, Henrik Grönberg, Yii-Der Ida Chen, Guo Li, Jacques S Beckmann, Toby Johnson, Unnur Thorsteinsdottir, Maris Teder-Laving, Kay-Tee Khaw, Nicholas J Wareham, Jing Hua Zhao, Najaf Amin, Ben A Oostra, Aldi T Kraja, Michael A Province, L Adrienne Cupples, Nancy L Heard-Costa, Jaakko Kaprio, Samuli Ripatti, Ida Surakka, Francis S Collins, Jouko Saramies, Jaakko Tuomilehto, Antti Jula, Veikko Salomaa, Jeanette Erdmann, Christian Hengstenberg, Christina Loley, Heribert Schunkert, Claudia Lamina, H Erich Wichmann, Eva Albrecht, Christian Gieger, Andrew A Hicks, Asa Johansson, Peter P Pramstaller, Sekar Kathiresan, Elizabeth K Speliotes, Brenda Penninx, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, Ulf Gyllensten, Dorret I Boomsma, Harry Campbell, James F Wilson, Stephen J Chanock, Martin Farrall, Anuj Goel, Carolina Medina-Gomez, Fernando Rivadeneira, Karol Estrada, André G Uitterlinden, Albert Hofman, M Carola Zillikens, Martin den Heijer, Lambertus A Kiemeney, Andrea Maschio, Per Hall, Jonathan Tyrer, Alexander Teumer, Henry Völzke, Peter Kovacs, Anke Tönjes, Massimo Mangino, Tim D Spector, Caroline Hayward, Igor Rudan, Alistair S Hall, Nilesh J Samani, Antony Paul Attwood, Jennifer G Sambrook, Joseph Hung, Lyle J Palmer, Marja-Liisa Lokki, Juha Sinisalo, Gabrielle Boucher, Heikki Huikuri, Mattias Lorentzon, Claes Ohlsson, Niina Eklund, Johan G Eriksson, Cristina Barlassina, Carlo Rivolta, Ilja M Nolte, Harold Snieder, Melanie M Van der Klauw, Jana V Van Vliet-Ostaptchouk, Pablo V Gejman, Jianxin Shi, Kevin B Jacobs, Zhaoming Wang, Stephan J L Bakker, Irene Mateo Leach, Gerjan Navis, Pim van der Harst, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Jian Yang, Daniel I Chasman, Paul M Ridker, Lynda M Rose, Terho Lehtimäki, Olli Raitakari, Devin Absher, Carlos Iribarren, Hanneke Basart, Kees G Hovingh, Elina Hyppönen, Chris Power, Denise Anderson, John P Beilby, Jennie Hui, Jennifer Jolley, Hendrik Sager, Stefan R Bornstein, Peter E H Schwarz, Kati Kristiansson, Markus Perola, Jaana Lindström, Amy J Swift, Matti Uusitupa, Mustafa Atalay, Timo A Lakka, Rainer Rauramaa, Jennifer L Bolton, Gerry Fowkes, Ross M Fraser, Jackie F Price, Krista Fischer, Kaarel Krjutå Kov, Andres Metspalu, Evelin Mihailov, Claudia Langenberg, Jian'an Luan, Ken K Ong, Peter S Chines, Sirkka M Keinanen-Kiukaanniemi, Timo E Saaristo, Sarah Edkins, Paul W Franks, Göran Hallmans, Dmitry Shungin, Andrew David Morris, Colin N A Palmer, Raimund Erbel, Susanne Moebus, Markus M Nöthen, Sonali Pechlivanis, Kristian Hveem, Narisu Narisu, Anders Hamsten, Steve E Humphries, Rona J Strawbridge, Elena Tremoli, Harald Grallert, Barbara Thorand, Thomas Illig, Wolfgang Koenig, Martina Müller-Nurasyid, Annette Peters, Bernhard O Boehm, Marcus E Kleber, Winfried März, Bernhard R Winkelmann, Johanna Kuusisto, Markku Laakso, Dominique Arveiler, Giancarlo Cesana, Kari Kuulasmaa, Jarmo Virtamo, John W G Yarnell, Diana Kuh, Andrew Wong, Lars Lind, Ulf de Faire, Bruna Gigante, Patrik K E Magnusson, Nancy L Pedersen, George Dedoussis, Maria Dimitriou, Genovefa Kolovou, Stavroula Kanoni, Kathleen Stirrups, Lori L Bonnycastle, Inger Njølstad, Tom Wilsgaard, Andrea Ganna, Emil Rehnberg, Aroon Hingorani, Mika Kivimaki, Meena Kumari, Themistocles L Assimes, Inês Barroso, Michael Boehnke, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Timothy Frayling, Leif C Groop, Talin Haritunians, David Hunter, Erik Ingelsson, Robert Kaplan, Karen L Mohlke, Jeffrey R O'Connell, David Schlessinger, David P Strachan, Kari Stefansson, Cornelia M van Duijn, Gonçalo R Abecasis, Mark I McCarthy, Joel N Hirschhorn, Lu Qi, Ruth J F Loos, Cecilia M Lindgren, Kari E North, Iris M Heid

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