Showing 1 - 11 results of 11 for search 'Alexander Hoffmann', query time: 0.02s Refine Results
  1. 1
    Protocol for the imputation of stimulus-induced single-cell gene expression trajectories from time-series scRNA-seq data

    Protocol for the imputation of stimulus-induced single-cell gene expression trajectories from time-series scRNA-seq data by Katherine M. Sheu, Alexander Hoffmann

    Published 2025-06-01
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  2. 2
    Understanding NF‐κB signaling via mathematical modeling

    Understanding NF‐κB signaling via mathematical modeling by Raymond Cheong, Alexander Hoffmann, Andre Levchenko

    Published 2008-05-01
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  3. 3
    A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling

    A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling by Emily R. Bozich, Xiaolu Guo, Jennifer L. Wilson, Alexander Hoffmann

    Published 2025-08-01
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  4. 4
    Modeling heterogeneous signaling dynamics of macrophages reveals principles of information transmission in stimulus responses

    Modeling heterogeneous signaling dynamics of macrophages reveals principles of information transmission in stimulus responses by Xiaolu Guo, Adewunmi Adelaja, Apeksha Singh, Roy Wollman, Alexander Hoffmann

    Published 2025-07-01
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  5. 5
    Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell population expansion

    Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell population expansion by Helen Huang, Haripriya Vaidehi Narayanan, Mark Yankai Xiang, Vaibhava Kesarwani, Alexander Hoffmann

    Published 2025-06-01
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  6. 6
    An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions

    An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions by Marie Oliver Metzig, Ying Tang, Simon Mitchell, Brooks Taylor, Robert Foreman, Roy Wollman, Alexander Hoffmann

    Published 2020-12-01
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  7. 7
    A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide

    A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide by Maxim N Shokhirev, Jonathan Almaden, Jeremy Davis‐Turak, Harry A Birnbaum, Theresa M Russell, Jesse A D Vargas, Alexander Hoffmann

    Published 2015-02-01
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  8. 8
    A homeostatic model of IκB metabolism to control constitutive NF‐κB activity

    A homeostatic model of IκB metabolism to control constitutive NF‐κB activity by Ellen L O'Dea, Derren Barken, Raechel Q Peralta, Kim T Tran, Shannon L Werner, Jeffrey D Kearns, Andre Levchenko, Alexander Hoffmann

    Published 2007-05-01
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  9. 9
    A stimulus‐contingent positive feedback loop enables IFN‐β dose‐dependent activation of pro‐inflammatory genes

    A stimulus‐contingent positive feedback loop enables IFN‐β dose‐dependent activation of pro‐inflammatory genes by Catera L Wilder, Diane Lefaudeux, Raisa Mathenge, Kensei Kishimoto, Alma Zuniga Munoz, Minh A Nguyen, Aaron S Meyer, Quen J Cheng, Alexander Hoffmann

    Published 2023-03-01
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  10. 10
    Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis.

    Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. by Kristyn E Feldman, Paul M Loriaux, Mayuko Saito, Iskra Tuero, Homarh Villaverde, Tenaya Siva, Eduardo Gotuzzo, Robert H Gilman, Alexander Hoffmann, Joseph M Vinetz

    Published 2013-01-01
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  11. 11
    Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL

    Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL by Aimilia Vareli, Haripriya Vaidehi Narayanan, Heather Clark, Eleanor Jayawant, Hui Zhou, Yi Liu, Emma Kennedy, Lauren Stott, Fabio Simoes, Alexander Hoffmann, Andrea Pepper, Chris Pepper, Simon Mitchell

    Published 2025-08-01
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