Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. by Sudagar S Gurcha, Veeraraghavan Usha, Jonathan A G Cox, Klaus Fütterer, Katherine A Abrahams, Apoorva Bhatt, Luke J Alderwick, Robert C Reynolds, Nicholas J Loman, VijayaShankar Nataraj, Carlos Alemparte, David Barros, Adrian J Lloyd, Lluis Ballell, Judith V Hobrath, Gurdyal S Besra

Get full text

Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3 by Catherine E. Rowland, Hector Newman, Tazmin T. Martin, Rachel Dods, Nikolaos Bournakas, James M. Wagstaff, Nick Lewis, Steven J. Stanway, Matthew Balmforth, Celia Kessler, Katerine van Rietschoten, Dom Bellini, David I. Roper, Adrian J. Lloyd, Christopher G. Dowson, Michael J. Skynner, Paul Beswick, Michael J. Dawson

Get full text